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糖尿病大鼠的热痛觉阈值的快速测定

Journal JoVE
Neurosciences

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Journal JoVE Neurosciences

Rapid Determination of the Thermal Nociceptive Threshold in Diabetic Rats

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糖尿病大鼠的热痛觉阈值的快速测定

27,215 Views

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05:45 min

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May 17, 2012

DOI:

DOI:

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05:45 min

May 17, 2012

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12 Views

Saeed Alshahrani¹, Filipe Fernandez-Conti², Amanda Araujo², Mauricio DiFulvio¹

¹Department of Pharmacology and Toxicology,Wright State University, ²Human Movement Laboratory,Universidade São Judas Tadeu

Summary

在这里，我们描述了一个快速可靠和简单的程序来确定的最低温度时大鼠或小鼠显示nocifensive的的行为，<em>即</em>“<em>热痛觉阈值</em>（梯恩梯）。这种方法适用于任何一个缓慢增长的热刺激，使精确，重现性与最低估计TNTs之应力的动物。

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