Journal
Médecine
Treating Immunoglobulin A Nephropathy (IgAN) with Dioscin in a Murine Model

Treating Immunoglobulin A Nephropathy (IgAN) with Dioscin in a Murine Model

October 13, 2023

Dioscin Mediated IgA Nephropathy Alleviation by Inhibiting B Cell Activation In Vivo and Decreasing Galactose-Deficient IgA1 Production In Vitro

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1Department of Nephrology,Guanganmen Hospital, 2Department of Nephrology,906 Hospital of Joint Logistic Support Force of People’s Liberation Army (PLA), 3Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences

Summary

This study provides experimental data for treating immunoglobulin A nephropathy (IgAN) with Dioscin (DIO), the active ingredient of Dioscoreae Nipponicae Rhizoma (DNR), and a paradigm for studying herbal medicine’s effects and underlying mechanisms in vivo and in vitro.

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