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小鼠常母离体肝机灌注

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Ingeniería
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JoVE Revista Ingeniería

Normothermic Ex Vivo Liver Machine Perfusion in Mouse

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小鼠常母离体肝机灌注

DOI:

10.3791/65363-v

•

13:14 min

•

September 25, 2023

•

Haotian Chen, Olaf Dirsch, Mohamed Albadry³, Paz Hernandez Ana, Uta Dahmen

¹Experimental Transplantation Surgery, Department of General, Visceral and Vascular Surgery,Jena University Hospital, ²Institute of Pathology,Klinikum Chemnitz GmbH, ³Department of Pathology, Faculty of Veterinary Medicine,Menoufia University

Capítulos

00:09Introduction
00:40Preparation
04:33Liver Explanation
09:49Liver and Chamber Connection
10:53Adjust the Flow Rate According to PV Pressure
11:19Representative Results
12:23Conclusion

Summary

Traducción Automática

为小鼠肝脏创建了常温离体肝灌注（NEVLP）系统。该系统需要显微外科手术经验，但允许可重复的灌注结果。利用小鼠肝脏的能力有助于研究分子途径以鉴定新型灌注添加剂，并能够执行专注于器官修复的实验。

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