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细胞性谷胱甘肽S-转移酶潜在抑制剂的分光光度筛选
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October 10, 2020
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1Research platform of Pediatric Onco-Hematology, Department of Paediatrics, Gynaecology and Obstetrics, Faculty of Medicine,University of Geneva, 2Section of Biology, Faculty of Science,University of Geneva, 3Onco-Hematology Unit, Department of Women, Children-Adolescents,University Hospitals of Geneva
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谷胱甘肽S-转移酶（GSTs）是参与许多化疗药物代谢的解毒酶。GSTs的表达与癌症化疗的抗性相关。对抗这种表型的一个方法就是使用抑制剂。该协议描述了一种使用分光光度测定来筛选潜在GST抑制剂的方法。
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Cite this Article
Robin, S. K. D., Ansari, M., Uppugunduri, C. R. S. Spectrophotometric Screening for Potential Inhibitors of Cytosolic Glutathione S-Transferases. J. Vis. Exp. (164), e61347, doi:10.3791/61347 (2020).
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