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Investigación sobre el cáncer

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毛尿胰腺腺腺腺癌超声引导正射植入

JoVE Revista
Investigación sobre el cáncer

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JoVE Revista Investigación sobre el cáncer

Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma

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毛尿胰腺腺腺腺癌超声引导正射植入

10,367 Views

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06:21 min

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November 19, 2019

DOI:

10.3791/60497-v

DOI:

10.3791/60497-v

•

06:21 min

November 19, 2019

•

10 Views

Ceire A. Hay¹, Rina Sor^2,3, Ahron J. Flowers^2,3, Cynthia Clendenin^2,3, Katelyn T. Byrne^1,4

¹Department of Medicine, Perelman School of Medicine,University of Pennsylvania, ²Pancreatic Cancer Mouse Hospital, Perelman School of Medicine,University of Pennsylvania, ³Abramson Cancer Center, Perelman School of Medicine,University of Pennsylvania, ⁴Parker Institute for Cancer Immunotherapy, Perelman School of Medicine,University of Pennsylvania

Summary

我们描述了一种将鼠源胰腺腺腺腺腺腺癌细胞系直接植入原生肿瘤部位的超声引导植入方案。与手术正交植入相比，这种方法在注射后2-4周内通过超声波扫描检测胰腺肿瘤，显著降低了围肠壁上肿瘤细胞播种的比例。

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