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腫瘍特異的 CD8+ T 細胞応答における Immunodominance を研究するためのインビボ細胞毒性アッセイ
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Inmunología y contagio
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JoVE Revista Inmunología y contagio
Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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腫瘍特異的 CD8+ T 細胞応答における Immunodominance を研究するためのインビボ細胞毒性アッセイ

8,686 Views

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10:13 min

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May 06, 2019

DOI:

10.3791/59531-v

DOI:
10.3791/59531-v

•

10:13 min
May 06, 2019

•

5 Views
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1Department of Microbiology and Immunology,Western University, 2Department of Medicine, Division of Clinical Immunology and Allergy,Western University, 3Department of Surgery, Division of General Surgery,Western University, 4Lawson Health Research Institute

Tags

In Vivo Cytotoxicity AssayTumor-specific CD8+ T Cell ResponsesImmunodominanceTumor AntigensCytotoxic T Cell ResponsesNK CellsInnate-like T LymphocytesAdherent Tumor Cell LineTarget Splenocyte PreparationC57BL/6 Mice

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Choi, J., Meilleur, C. E., Haeryfar, S. M. Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses. J. Vis. Exp. (147), e59531, doi:10.3791/59531 (2019).

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