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小鼠肾小球疾病模型肾脏功能的评价

JoVE Revista
Medicina

This content is Free Access.

JoVE Revista Medicina

Assessment of Kidney Function in Mouse Models of Glomerular Disease

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小鼠肾小球疾病模型肾脏功能的评价

DOI:

10.3791/57764-v

•

09:16 min

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June 30, 2018

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Megan Stevens^2,3, Sebastian Oltean^2,3

¹Institute of Biomedical and Clinical Sciences, Medical School,University of Exeter, ²School of Physiology, Pharmacology and Neurosciences,University of Bristol, ³Bristol Renal, School of Clinical Sciences,University of Bristol

Capítulos

00:04Título
00:30Sample Collection and Preparation for Analysis
03:27Glomeruli Isolation and Glomerular Water Permeability (LpA/Vi)
05:36Periodic Acid Schiff (PAS) Stain
06:55Results: Representative Kidney Function Assessment
08:55Conclusion

Summary

Traducción Automática

本议定书描述了肾小球疾病小鼠模型中应进行的全肾脏工作。这些方法可以对肾小球疾病的所有小鼠模型进行详细的功能、结构和机械分析。

Tags

Keywords: Kidney Function Mouse Model Glomerular Disease Urinary Albumin Creatinine Ratio Cortical Glomeruli Juxtamedullary Glomeruli Histology Immunofluorochemical Analysis Protein Analysis RNA Analysis Glomeruli Isolation

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