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Temporal Упорядочение динамических данных выражений из конкретных пространственных Expression Maps
JoVE Revista
Biología del desarrollo
This content is Free Access.
JoVE Revista Biología del desarrollo
Temporal Ordering of Dynamic Expression Data from Detailed Spatial Expression Maps

Temporal Упорядочение динамических данных выражений из конкретных пространственных Expression Maps

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11:52 min

February 09, 2017

DOI:

11:52 min
February 09, 2017

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Summary

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The segmentation clock drives oscillatory gene expression across the pre-somitic mesoderm (PSM). Dynamic Notch activity is key to this process. We use imaging and computational analyses to extract temporal dynamics from spatial expression data to demonstrate that Delta ligand and Notch receptor expression oscillate in the vertebrate PSM.

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