We present a method for achieving sub-nanometer resolution images with amplitude-modulation (tapping mode) atomic force microscopy in liquid. The method is demonstrated on commercial atomic force microscopes. We explain the rationale behind our choices of parameters and suggest strategies for resolution optimization.
Miller, E. J., Trewby, W., Farokh Payam, A., Piantanida, L., Cafolla, C., Voïtchovsky, K. Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid. J. Vis. Exp. (118), e54924, doi:10.3791/54924 (2016).