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Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
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Capítulos
- 00:05Título
- 00:55Mouse BCG Vaccination and Mycobacterium tuberculosis Challenge
- 02:18Bronchoalveolar Lavage (BAL) Sample Acquisition
- 04:11Results: Representative Vaccine-specific Pulmonary Immune Response Analyses
- 05:46Conclusion
We herein detail the methodology followed to compare protective efficacy and lung immune response induced by intranasal and subcutaneous immunization with BCG in mouse model. Our results show the benefits of pulmonary vaccination and suggest a role for IL17-mediated response in vaccine-induced protection.
