Journal
/
Quimica
/
の合成のためのプロトコル<em>オルソ</em> -trifluoromethoxylatedアニリン誘導体
JoVE Revista
Quimica
Se requiere una suscripción a JoVE para ver este contenido.  Inicie sesión o comience su prueba gratuita.
JoVE Revista Quimica
Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
Please note that all translations are automatically generated. Click here for the English version.

の合成のためのプロトコル<em>オルソ</em> -trifluoromethoxylatedアニリン誘導体

9,731 Views

•

08:43 min

•

January 19, 2016

DOI:

10.3791/53789-v

DOI:
10.3791/53789-v

•

08:43 min
January 19, 2016

•

2 Views
,
1Department of Chemistry,State University of New York at Stony Brook, 2Institute of Chemical Biology and Drug Discovery,State University of New York at Stony Brook

Summary

Automatically generated

An operationally simple procedure for the synthesis of ortho-trifluoromethoxylated aniline derivatives via a two-step sequence of O-trifluoromethylation of N-aryl-N-hydroxyacetamide followed by thermally induced intramolecular OCF3-migration is reported.

Explore More Videos

Ortho-trifluoromethoxylated AnilineAniline DerivativesReductionHydrogenationAcetyl ProtectionRhodium CatalystCelite FiltrationTLC MonitoringAnhydrous SolventsNitrogen Atmosphere

Read Article

Cite this Article

Feng, P., Ngai, M. Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives. J. Vis. Exp. (107), e53789, doi:10.3791/53789 (2016).

Download .ris file

Copy

Share Video

.

Copy