Oprichting van een Segmentale Femorale Critical-size Defect Model in Muizen gestabiliseerd door plaatosteosynthese

Although mouse models are invaluable tools for bone tissue engineering, models of long bone defects are sparse. This need motivated development of the present protocol which uses a locking plate with four screws and a dedicated jig to perform and stabilize a reproducible, femoral, critical-size defect with low morbidity.