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髄質胸腺上皮細胞の増殖、分化および無差別遺伝子発現を支える3D器官共培養モデル
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JoVE Revista Biología del desarrollo
3D Organotypic Co-culture Model Supporting Medullary Thymic Epithelial Cell Proliferation, Differentiation and Promiscuous Gene Expression
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髄質胸腺上皮細胞の増殖、分化および無差別遺伝子発現を支える3D器官共培養モデル

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06:47 min

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July 30, 2015

DOI:

10.3791/52614-v

DOI:
10.3791/52614-v

•

06:47 min
July 30, 2015

•

12 Views
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1Division of Developmental Immunology,German Cancer Research Center (DKFZ), 2Genetics of Skin Carcinogenesis,German Cancer Research Center (DKFZ)

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3D Organotypic Co-culture ModelMedullary Thymic Epithelial Cells (mTECs)Promiscuous Gene ExpressionT Cell DevelopmentSelf-toleranceRANKLFoxN1AireCortical Thymic Epithelial Cells (cTECs)

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Pinto, S., Stark, H., Martin, I., Boukamp, P., Kyewski, B. 3D Organotypic Co-culture Model Supporting Medullary Thymic Epithelial Cell Proliferation, Differentiation and Promiscuous Gene Expression. J. Vis. Exp. (101), e52614, doi:10.3791/52614 (2015).

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