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Forward Genetica schermi usando macrofagi per identificare<em> Toxoplasma gondii</em> geni importanti per la Resistenza di IFN-γ-Dependent cellulare Immunità autonoma
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Forward Genetica schermi usando macrofagi per identificare<em> Toxoplasma gondii</em> geni importanti per la Resistenza di IFN-γ-Dependent cellulare Immunità autonoma
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March 12, 2015
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Forward genetics is a powerful approach to identify genes in intracellular pathogens important for resistance to cell autonomous immunity. The current approach uses innate immune cells, specifically macrophages, to identify novel Toxoplasma gondii genes important for immune evasion.
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Walwyn, O., Skariah, S., Lynch, B., Kim, N., Ueda, Y., Vohora, N., Choe, J., Mordue, D. G. Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity. J. Vis. Exp. (97), e52556, doi:10.3791/52556 (2015).
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