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可燃たばこ製品製剤の細胞毒性および免疫抑制を評価するための方法
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January 10, 2015
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Using optimized human peripheral blood mononuclear cell (PBMC) ex vivo assays, we showed that a combustible tobacco product preparation markedly suppresses receptor-mediated intracellularly secreted cytokines and cytolytic ability of effector PBMCs. These rapid assays may be useful in product evaluation and understanding the potential long-term effects of tobacco exposure.
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Arimilli, S., Damratoski, B. E., G.L., P. Methods to Evaluate Cytotoxicity and Immunosuppression of Combustible Tobacco Product Preparations. J. Vis. Exp. (95), e52351, doi:10.3791/52351 (2015).
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