/
/
Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
Se requiere una suscripción a JoVE para ver este contenido. Inicie sesión o comience su prueba gratuita.
Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
12,344 Views
•
17:28 min
•
June 17, 2015
DOI:
1Center of Physiology and Pathophysiology, Institute of Neurophysiology,University of Cologne, 2Department of Biology,University of Konstanz, 3Department of Statistics,Technical University of Dortmund, 4Leibniz Research Centre for Working Environment and Human Factors,Technical University of Dortmund
Tags
Human Pluripotent Stem CellsDevelopmental Toxicity AssaysChemical Safety ScreeningSystems BiologyEmbryonic Stem CellsEmbryoid BodiesNeuroectodermal Progenitor CellsTranscriptome MicroarrayIn Vitro Toxicity TestingEarly Embryonic ToxicityTeratogenicityDevelopmental NeurotoxicityEpigenetic ChangesToxicity BiomarkersSystems Biology AnalysisAnimal Studies ReductionDrug DevelopmentChemical Safety Evaluation
Read Article
Cite this Article
Shinde, V., Klima, S., Sureshkumar, P. S., Meganathan, K., Jagtap, S., Rempel, E., Rahnenführer, J., Hengstler, J. G., Waldmann, T., Hescheler, J., Leist, M., Sachinidis, A. Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation. J. Vis. Exp. (100), e52333, doi:10.3791/52333 (2015).
Copy