Sviluppo di un<em> In vitro</em> Sistema modello per studiare l'interazione tra<em> Equus</em><em> Caballus</em> IgE con il suo recettore ad alta affinità FcεRI
JoVE Revista
Inmunología y contagio Author Produced
The current study describes the development and applications of a genetically engineered assay system based on the transfection of rat basophilic leukemia cells with the equine FcεRIα gene. Transfected cells express a functional receptor where the release of mediators of the allergic response can be activated by IgE and antigen.