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전단 응력의 인간 간 사인 내피에서 조건에 백혈구 모집을 연구하는 흐름 접착 분석
JoVE Revista
Inmunología y contagio
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JoVE Revista Inmunología y contagio
A Flow Adhesion Assay to Study Leucocyte Recruitment to Human Hepatic Sinusoidal Endothelium Under Conditions of Shear Stress
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전단 응력의 인간 간 사인 내피에서 조건에 백혈구 모집을 연구하는 흐름 접착 분석

14,948 Views

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11:38 min

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March 21, 2014

DOI:

10.3791/51330-v

DOI:
10.3791/51330-v

•

11:38 min
March 21, 2014

•

1 Views
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1NIHR Biomedical Research Unit, Centre for Liver Research, School of Immunity and Infection,University of Birmingham

Tags

Flow Adhesion AssayLeucocyte RecruitmentHuman Hepatic Sinusoidal EndotheliumShear StressInflammatory Liver DiseasesFibrosisCirrhosisMolecular MechanismsTherapeutic TargetsLeucocyte InfiltrationHepatic SinusoidsHepatic Sinusoidal Endothelial Cells (HSEC)Adhesion CascadeTetheringActivationFirm AdhesionCrawlingTransmigrationPhase Contrast MicroscopyInhibitors

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Shetty, S., Weston, C. J., Adams, D. H., Lalor, P. F. A Flow Adhesion Assay to Study Leucocyte Recruitment to Human Hepatic Sinusoidal Endothelium Under Conditions of Shear Stress. J. Vis. Exp. (85), e51330, doi:10.3791/51330 (2014).

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