The present work provides a comprehensive set of guidelines for manually tracing the medial temporal lobe (MTL) structures. This protocol can be applied to research involving structural and/or combined structural-functional magnetic resonance imaging (MRI) investigations of the MTL, in both healthy and clinical groups.
Moore, M., Hu, Y., Woo, S., O'Hearn, D., Iordan, A. D., Dolcos, S., Dolcos, F. A Comprehensive Protocol for Manual Segmentation of the Medial Temporal Lobe Structures. J. Vis. Exp. (89), e50991, doi:10.3791/50991 (2014).