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NADH Fluorescence Imaging of Isolated Biventricular Working Rabbit Hearts
 

NADH Fluorescence Imaging of Isolated Biventricular Working Rabbit Hearts

Article DOI: 10.3791/4115-v • 12:07 min • July 24th, 2012
July 24th, 2012 •
1, 1, 1, 2, 1
1Electrical and Computer Engineering Department, The George Washington University, 2Pharmacology and Physiology Department, The George Washington University

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Resumen
Automatic Translation

The objective is to monitor the mitochondrial redox state of isolated hearts within the context of physiologic preload and afterload pressures. A biventricular working rabbit heart model is presented. High spatiotemporal resolution fluorescence imaging of NADH is used to monitor the mitochondrial redox state of epicardial tissue.

Tags

NADH Fluorescence Imaging Isolated Perfused Heart Langendorff Technique Cardiac Physiology Cardiac Metabolism LV Working Heart Model Biventricular Model Stroke Volume Cardiac Output Pressure Development Myocardial Injury Ischemia NADH Fluorescence
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