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Culture ex vivo des cellules humaines primaires épithéliales des trompes de Fallope
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May 09, 2011
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Les trompes de Fallope (FT) se profile comme un site alternatif d'origine d'un carcinome ovarien séreux (SOC). Ce protocole décrit une nouvelle méthode pour l'isolement et<em> Ex vivo</em> Culture de cellules épithéliales des trompes de Fallope. Ce système reprend le<em> In vivo</emL'épithélium> et permet l'étude de la pathogenèse du COS.
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Ex Vivo CulturePrimary Human Fallopian Tube Epithelial CellsEpithelial Ovarian CancerFemale Cancer MortalityUnited StatesBreast CarcinomaUterine CarcinomaOvarian Cancer Cure RatesScreening ToolsEarly Stage Disease DetectionSurgeryChemotherapyAdvanced Stage DiseaseDiffuse Abdominal InvolvementHeterogeneous DiseaseHistologic SubtypesSerous Ovarian Carcinoma (SOC)BRCA Genes MutationsExperimental ModelsCancer Cell LinesMouse ModelsInitiating Genetic EventsPathogenesis Of DiseaseFallopian Tube Origin Of SOCFallopian Tube Secretory Epithelial Cell (FTSEC)Cell Lines Culture Systems
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Fotheringham, S., Levanon, K., Drapkin, R. Ex Vivo Culture of Primary Human Fallopian Tube Epithelial Cells. J. Vis. Exp. (51), e2728, doi:10.3791/2728 (2011).
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