Waiting
Procesando inicio de sesión ...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / An Orthotopic Model of Serous Ovarian Cancer in…
JoVE Journal
Immunology and Infection

Se requiere una suscripción a JoVE para ver este contenido. Inicie sesión o comience su prueba gratuita.

JoVE Journal Immunology and Infection
An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses
 

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses

Article DOI: 10.3791/2146-v • 10:35 min • November 28th, 2010
November 28th, 2010 •
1, 2, 1
1Penn Ovarian Cancer Research Center, Center for Research on Reproduction and Womans Health, Department of Obstetrics and Gynecology, University of Pennsylvania-School of Medicine, 2Women's Cancer Program, Fox Chase Cancer Center

Capítulos

Resumen
Automatic Translation

To study in vivo tumor growth and tumor microenvironment, we used a syngeneic and orthotopic mouse model of ovarian cancer in immunocompetent animals. We transduced a mouse tumor cell line (MOV1) with Katushka fluorescent protein (MOV1KAT) and here we show its orthotopic implantation in ovary and in vivo imaging.

Tags

Orthotopic Model Serous Ovarian Cancer Immunocompetent Mice In Vivo Tumor Imaging Tumor Immune Responses Tg-MISIIR-TAg Transgenic Mouse Model SV40 Transforming Region Mullerian Inhibitory Substance Type II Receptor (MISIIR) Gene Promoter Syngeneic Allograft Recipients Preclinical Studies Tumor Microenvironment
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter