Using 23Na Magnetic Resonance Imaging to Measure Sodium in Muscle Tissues
Published: February 29, 2024
Abstract
This video demonstrates the quantification of sodium content in human tissues using sodium magnetic resonance imaging (23Na-MRI). The patient's lower leg is placed within the radiofrequency (RF) coil of the machine, and a three-dimensional gradient-echo sequence is performed. Multinuclear MRI images are generated using hydrogen and sodium nuclei to quantify sodium levels in various tissues.
Protocol
All procedures involving human participants have been performed in compliance with the institutional, national, and international guidelines for human welfare and have been reviewed by the local institutional review board. 1. Preparation of the phantom holder Four standard sodium solutions, including aqueous NaCl in the physiologic range of peripheral tissue sodium content 10-40 mmol/L, are embedded in a platform in the coil. <stron…
Divulgaciones
The authors have nothing to disclose.
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Using 23Na Magnetic Resonance Imaging to Measure Sodium in Muscle Tissues. J. Vis. Exp. (Pending Publication), e22207, doi: (2024).