FDG Based PET/CT Scan: A Method of Using Radiotracer for Non-invasive Imaging of Tumor Metabolism
Published: April 30, 2023
Abstract
Source: Momcilovic M. et al., Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer. J. Vis. Exp. (2018)
This article describes multimodality imaging of cancerous tissues with PET and CT diagnostic imaging by using a radiotracer 18F-FDG. Cancerous tissue with high glycolytic activity uptakes more 18F-FDG.
Protocol
All procedures involving animals have been reviewed by the local institutional animal care committee and the JoVE veterinary review board. 1.18F-FDG PET and CT Imaging in Mice CAUTION: Use protective equipment when handling radioactivity. Follow all applicable regulatory procedures when handling radioactivity. Place the cage with the mice to be imaged on a warm bed at 37 °C 1 h prior to the 18</…
Divulgaciones
The authors have nothing to disclose.
Materials
| G8 PET/CT | Perkin Elmer | CLS139564 | Used for 18F-FDG PET and CT imaging of mice |
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FDG Based PET/CT Scan: A Method of Using Radiotracer for Non-invasive Imaging of Tumor Metabolism. J. Vis. Exp. (Pending Publication), e20242, doi: (2023).