JOVE JOURNAL

Investigación sobre el cáncer

Showing 13 - 24 in 611 videos.

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Journal (Cancer Research)

Assessment of DNA Double Strand Break Repair Activity Using High-throughput and Quantitative Luminescence-Based Reporter Assays

Diego Grande*¹, Eeson Rajendra*¹, Bethany Mason¹, Alessandro Galbiati¹, Simon J. Boulton^1,2, Graeme C. M. Smith¹, Helen M. R. Robinson¹

¹Artios Pharma Ltd, Cambridge, ²The Francis Crick Institute, London

Journal (Cancer Research)

Development of Hypoxia-Responsive CAR-T Cells via Lentiviral Transduction

Ying Xue*¹, Yunyu Mao*², Qibin Liao³, Chen Zhao⁴, Xiaoyan Zhang^1,2,4, Jianqing Xu^1,2,4

¹Institutes of Biomedical Sciences,Fudan University, ²Clinical Center of Biotherapy at Zhongshan Hospital,Fudan University, ³Department of Oncology and Bio-therapeutic Center, Shenzhen Third People's Hospital,Southern University of Science and Technology, ⁴Shanghai Public Health Clinical Center,Fudan University

Journal (Cancer Research)

Flow Cytometric Assessment of Oxygen-Dependent CAR Expression in CAR-T Cells

Ying Xue*¹, Yunyu Mao*², Qibin Liao³, Chen Zhao⁴, Xiaoyan Zhang^1,2,4, Jianqing Xu^1,2,4

¹Institutes of Biomedical Sciences,Fudan University, ²Clinical Center of Biotherapy at Zhongshan Hospital,Fudan University, ³Department of Oncology and Bio-therapeutic Center, Shenzhen Third People's Hospital,Southern University of Science and Technology, ⁴Shanghai Public Health Clinical Center,Fudan University

Journal (Cancer Research)

In Vitro Assessment of Cytotoxicity Mediated by Hypoxia-Sensitive CAR-T Cells

Ying Xue*¹, Yunyu Mao*², Qibin Liao³, Chen Zhao⁴, Xiaoyan Zhang^1,2,4, Jianqing Xu^1,2,4

¹Institutes of Biomedical Sciences,Fudan University, ²Clinical Center of Biotherapy at Zhongshan Hospital,Fudan University, ³Department of Oncology and Bio-therapeutic Center, Shenzhen Third People's Hospital,Southern University of Science and Technology, ⁴Shanghai Public Health Clinical Center,Fudan University

Journal (Cancer Research)

Identifying Neurofibromas and Malignant Peripheral Nerve Sheath Tumors (MPNSTs) in P₀-GGFβ3 Mice

Dorea P. Jenkins¹, Brittany Turner-Ivey^1,2, Jody Fromm Longo¹, Steven L. Carroll^1,2

¹Department of Pathology and Laboratory Medicine,Medical University of South Carolina, ²Hollings Cancer Center,Medical University of South Carolina

Journal (Cancer Research)

Preparing Hematoxylin and Eosin-Stained Sections of Grossly Visible Tumors

Dorea P. Jenkins¹, Brittany Turner-Ivey^1,2, Jody Fromm Longo¹, Steven L. Carroll^1,2

¹Department of Pathology and Laboratory Medicine,Medical University of South Carolina, ²Hollings Cancer Center,Medical University of South Carolina

Journal (Cancer Research)

Identifying Potential Plexiform Neurofibromas (PNs) and Malignant Peripheral Nerve Sheath Tumors (MPNSTs) by Performing Special Stains to Confirm Diagnoses

Dorea P. Jenkins¹, Brittany Turner-Ivey^1,2, Jody Fromm Longo¹, Steven L. Carroll^1,2

¹Department of Pathology and Laboratory Medicine,Medical University of South Carolina, ²Hollings Cancer Center,Medical University of South Carolina

Journal (Cancer Research)

Verifying the Identity of Early-Passage MPNST Cells and Allograft of Early-Passage Tumor Cells to Demonstrate Tumorigenicity

Dorea P. Jenkins¹, Brittany Turner-Ivey^1,2, Jody Fromm Longo¹, Steven L. Carroll^1,2

¹Department of Pathology and Laboratory Medicine,Medical University of South Carolina, ²Hollings Cancer Center,Medical University of South Carolina

Journal (Cancer Research)

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Dorea P. Jenkins¹, Brittany Turner-Ivey^1,2, Jody Fromm Longo¹, Steven L. Carroll^1,2

¹Department of Pathology and Laboratory Medicine,Medical University of South Carolina, ²Hollings Cancer Center,Medical University of South Carolina

Journal (Cancer Research)

Quantifying Antibody-Dependent Cellular Cytotoxicity in a Tumor Spheroid Model: Application for Drug Discovery

Isotta Sturniolo^1,2, Csongor Váróczy^1,3, Ákos Máté Bede^1,3, Csaba Hegedűs¹, Máté Á. Demény^1,4, László Virág^1,4

¹Department of Medical Chemistry, Faculty of Medicine,University of Debrecen, ²Doctoral School of Molecular Medicine,University of Debrecen, ³National Academy of Scientist Education, ⁴HUN-REN-DE Cell Biology and Signaling Research Group

Journal (Cancer Research)

Mast Cells in the Microenvironment of Hepatocellular Carcinoma Confer Favorable Prognosis: A Retrospective Study using QuPath Image Analysis Software

Esraa Ali¹, Lenka Červenková^2,3, Richard Pálek^2,4, Filip Ambrozkiewicz¹, Sergii Pavlov¹, Wenjing Ye¹, Petr Hošek², Ondrej Daum^5,6, Václav Liška^2,4, Kari Hemminki^1,7, Andriy Trailin¹

¹Laboratory of Translational Cancer Genomics, Biomedical Center, Faculty of Medicine in Pilsen,Charles University, ²Laboratory of Cancer Treatment and Tissue Regeneration, Biomedical Center, Faculty of Medicine in Pilsen,Charles University, ³Department of Pathology, Third Faculty of Medicine,Charles University, ⁴Department of Surgery and Biomedical Center, Faculty of Medicine in Pilsen,Charles University, ⁵Sikl's Institute of Pathology, Faculty of Medicine and Teaching Hospital in Pilsen,Charles University, ⁶Bioptická Laboratoř s.r.o., ⁷Department of Cancer Epidemiology,German Cancer Research Center

Journal (Cancer Research)

Image Analysis to Obtain Prognostic Information for Tumor-Infiltrating Immune Cells in Hepatocellular Carcinoma (HCC)

Esraa Ali¹, Lenka Červenková^2,3, Richard Pálek^2,4, Filip Ambrozkiewicz¹, Sergii Pavlov¹, Wenjing Ye¹, Petr Hošek², Ondrej Daum^5,6, Václav Liška^2,4, Kari Hemminki^1,7, Andriy Trailin¹

¹Laboratory of Translational Cancer Genomics, Biomedical Center, Faculty of Medicine in Pilsen,Charles University, ²Laboratory of Cancer Treatment and Tissue Regeneration, Biomedical Center, Faculty of Medicine in Pilsen,Charles University, ³Department of Pathology, Third Faculty of Medicine,Charles University, ⁴Department of Surgery and Biomedical Center, Faculty of Medicine in Pilsen,Charles University, ⁵Sikl's Institute of Pathology, Faculty of Medicine and Teaching Hospital in Pilsen,Charles University, ⁶Bioptická Laboratoř s.r.o., ⁷Department of Cancer Epidemiology,German Cancer Research Center

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