A Practical Guide to Phage- and Robotics-Assisted Near-Continuous Evolution

Samir Aoudjane; Stefan Golas; Osaid Ather; Michael J. Hammerling; Erika DeBenedictis

doi:10.3791/65974

Journal

Bioingeniería

Setting Up PRANCE: A Comprehensive Guide for Robotics-Accelerated Evolution

January 12, 2024

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

01:06 min

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678 Views

Pre-Run Preparation for Phage- and Robotics-Assisted Near-Continuous Evolution (PRANCE) Technique

01:46 min

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113 Views

Hardware and Software Integration to Perform Phage- and Robotics-Assisted Near-Continuous Evolution (PRANCE)

02:19 min

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127 Views

Samir Aoudjane¹, Stefan Golas², Osaid Ather¹, Michael J. Hammerling³, Erika DeBenedictis¹

¹The Francis Crick Institute, ²Massachusetts Institute of Technology, ³Future House

Summary

Phage- and Robotics-assisted Near-continuous Evolution (PRANCE) is a technique for rapid, robust protein evolution. Robotics allows the parallelization of experiments, real-time monitoring, and feedback control.

Setting Up PRANCE: A Comprehensive Guide for Robotics-Accelerated Evolution

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

Pre-Run Preparation for Phage- and Robotics-Assisted Near-Continuous Evolution (PRANCE) Technique

Hardware and Software Integration to Perform Phage- and Robotics-Assisted Near-Continuous Evolution (PRANCE)

Summary

Article