Multiplex Immunoassay for Borrelia-Specific IgG and IgM in Serum

July 14th, 2023

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Julia Häring*¹, Tanja Michel*¹, Matthias Becker¹, Daniel Junker¹, Tatia Tchitchagua², Olaf Leschnik², Berit Lange^3,4, Stefanie Castell^3,4, Gérard Krause^3,4, Monika Strengert³, Alex Dulovic¹, Nicole Schneiderhan-Marra¹

¹NMI Natural and Medical Sciences Institute at the University of Tübingen, ²Department of Neurology, Sächsisches Krankenhaus Rodewisch, ³Department of Epidemiology, Helmholtz Centre for Infection Research, ⁴German Centre for Infection Research (DZIF)

* These authors contributed equally

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Ein Dreikanal-Dual-Reporter-Fluoreszenz-Flussanalysesystem wurde verwendet, um einen Bead-basierten Multiplex-Immunoassay zu entwickeln, der gleichzeitig Serumproben auf IgG und IgM auswertet, die gegen mehrere Antigene verschiedener Borrelienspezies extrahiert wurden, die die Lyme-Borreliose in Europa und Nordamerika verursachen.

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Multiplex Immunoassay for Borrelia-Specific IgG and IgM in Serum

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