Günther Schlunck Eye Center, Medical Center - University of Freiburg, Faculty of Medicine University of Freiburg Biography Publications Institution JoVE Articles Günther Schlunck has not added a biography. If you are Günther Schlunck and would like to personalize this page please email our Author Liaison for assistance. Publications Enrichment, Characterization, and Proteomic Profiling of Small Extracellular Vesicles Derived from Human Limbal Mesenchymal Stromal Cells and Melanocytes Cells. Apr, 2024 | Pubmed ID: 38607062 The Impact of Substrate Stiffness on Morphological, Transcriptional and Functional Aspects in RPE Scientific Reports. Mar, 2024 | Pubmed ID: 38553490 2D and 3D in Vitro Angiogenesis Assays Highlight Different Aspects of Angiogenesis Biochimica Et Biophysica Acta. Molecular Basis of Disease. Mar, 2024 | Pubmed ID: 38244944 Oncostatin M Reduces Pathological Neovascularization in the Retina Through Müller Cell Activation Investigative Ophthalmology & Visual Science. Jan, 2024 | Pubmed ID: 38190125 Transcriptional Profiling Specifies the Pathogen-specific Human Host Response to Infectious Keratitis Frontiers in Cellular and Infection Microbiology. 2023 | Pubmed ID: 38274739 Addressing Bias in Manual Segmentation of Spheroid Sprouting Assays with U-Net Molecular Vision. 2023 | Pubmed ID: 38222450 Transcriptional Comparison of Human and Murine Retinal Neovascularization Investigative Ophthalmology & Visual Science. Dec, 2023 | Pubmed ID: 38153746 Influence of Organ Culture on the Characteristics of the Human Limbal Stem Cell Niche International Journal of Molecular Sciences. Nov, 2023 | Pubmed ID: 38069177 Slow Interstitial Fluid Flow Activates TGF-β Signaling and Drives Fibrotic Responses in Human Tenon Fibroblasts Cells. Sep, 2023 | Pubmed ID: 37681937 Characterization of the Immediate and Delayed Biomechanical Response to UV-A Crosslinking of Human Corneas Cornea. Sep, 2023 | Pubmed ID: 37335854 Efficient Isolation and Expansion of Limbal Melanocytes for Tissue Engineering International Journal of Molecular Sciences. Apr, 2023 | Pubmed ID: 37175529 Characterization of Porcine Ocular Surface Epithelial Microenvironment International Journal of Molecular Sciences. Apr, 2023 | Pubmed ID: 37108705 PAX6 Expression Patterns in the Adult Human Limbal Stem Cell Niche Cells. Jan, 2023 | Pubmed ID: 36766742 Transcriptional Profiling Identifies Prognostic Gene Signatures for Conjunctival Extranodal Marginal Zone Lymphoma Biomolecules. Jan, 2023 | Pubmed ID: 36671500 STAT3 Signaling Induced by the IL-6 Family of Cytokines Modulates Angiogenesis Journal of Cell Science. Jan, 2023 | Pubmed ID: 36458801 Web-based Gene Expression Analysis-paving the Way to Decode Healthy and Diseased Ocular Tissue Die Ophthalmologie. Jan, 2023 | Pubmed ID: 36098765 Transcriptional Profiling Provides New Insights into Organ Culture-Induced Changes in Human Donor Corneas International Journal of Molecular Sciences. Nov, 2022 | Pubmed ID: 36498835 Transcriptomic Landscape and Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Limbal Epithelial Progenitor Cells Cells. Nov, 2022 | Pubmed ID: 36497012 [Next-generation Sequencing in Ophthalmology] Die Ophthalmologie. Dec, 2022 | Pubmed ID: 36418561 Isolation and Expansion of Limbal Mesenchymal Stromal Cells Bio-protocol. Jul, 2022 | Pubmed ID: 35978577 Methylglyoxal and High Glucose Inhibit VEGFR2 Phosphorylation at Specific Tyrosine Residues Zeitschrift Fur Naturforschung. C, Journal of Biosciences. Nov, 2022 | Pubmed ID: 35767310 P-Cadherin Is Expressed by Epithelial Progenitor Cells and Melanocytes in the Human Corneal Limbus Cells. Jun, 2022 | Pubmed ID: 35741104 Inhalative As Well As Intravenous Administration of HS Provides Neuroprotection After Ischemia and Reperfusion Injury in the Rats' Retina International Journal of Molecular Sciences. May, 2022 | Pubmed ID: 35628328 Single-Cell Protein and Transcriptional Characterization of Epiretinal Membranes From Patients With Proliferative Vitreoretinopathy Investigative Ophthalmology & Visual Science. May, 2022 | Pubmed ID: 35579905 Transcriptional and Distributional Profiling of Microglia in Retinal Angiomatous Proliferation International Journal of Molecular Sciences. Mar, 2022 | Pubmed ID: 35408803 In-Depth Molecular Profiling Specifies Human Retinal Microglia Identity Frontiers in Immunology. 2022 | Pubmed ID: 35371110 Efficient Isolation and Functional Characterization of Niche Cells from Human Corneal Limbus International Journal of Molecular Sciences. Mar, 2022 | Pubmed ID: 35269891 Deciphering the Molecular Signature of Human Hyalocytes in Relation to Other Innate Immune Cell Populations Investigative Ophthalmology & Visual Science. Mar, 2022 | Pubmed ID: 35266958 The Human Eye Transcriptome Atlas: A Searchable Comparative Transcriptome Database for Healthy and Diseased Human Eye Tissue Genomics. Mar, 2022 | Pubmed ID: 35124170 Comparative Transcriptome Analysis of Human and Murine Choroidal Neovascularization Identifies Fibroblast Growth Factor Inducible-14 As Phylogenetically Conserved Mediator of Neovascular Age-related Macular Degeneration Biochimica Et Biophysica Acta. Molecular Basis of Disease. Apr, 2022 | Pubmed ID: 35032596 Subretinal Fibrosis in Neovascular Age-related Macular Degeneration: Current Concepts, Therapeutic Avenues, and Future Perspectives Cell and Tissue Research. Mar, 2022 | Pubmed ID: 34477966 Time- and Stimulus-Dependent Characteristics of Innate Immune Cells in Organ-Cultured Human Corneal Tissue Journal of Innate Immunity. 2022 | Pubmed ID: 34182556 Characterization of the Cellular Microenvironment and Novel Specific Biomarkers in Pterygia Using RNA Sequencing Frontiers in Medicine. 2021 | Pubmed ID: 35174178 Immunosenescence in Choroidal Neovascularization (CNV)-Transcriptional Profiling of Naïve and CNV-Associated Retinal Myeloid Cells During Aging International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 34948115 Viral S Protein Histochemistry Reveals Few Potential SARS-CoV-2 Entry Sites in Human Ocular Tissues Scientific Reports. Sep, 2021 | Pubmed ID: 34580409 Hydrogen Sulfide Reduces Ischemia and Reperfusion Injury in Neuronal Cells in a Dose- and Time-Dependent Manner International Journal of Molecular Sciences. Sep, 2021 | Pubmed ID: 34576259 A Decellularized Human Limbal Scaffold for Limbal Stem Cell Niche Reconstruction International Journal of Molecular Sciences. Sep, 2021 | Pubmed ID: 34576227 The Role of Interferon Regulatory Factor 8 for Retinal Tissue Homeostasis and Development of Choroidal Neovascularisation Journal of Neuroinflammation. Sep, 2021 | Pubmed ID: 34544421 Imaging Mass Cytometry for High-dimensional Tissue Profiling in the Eye BMC Ophthalmology. Sep, 2021 | Pubmed ID: 34544377 A Decellularized Human Corneal Scaffold for Anterior Corneal Surface Reconstruction Scientific Reports. Feb, 2021 | Pubmed ID: 33542377 What is the Significance of the Conjunctiva As A potential Transmission Route for SARS-CoV-2 Infections? Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft. Jan, 2021 | Pubmed ID: 33141332 Different Innate Immune Responses in BALB/c and C57BL/6 Strains Following Corneal Transplantation Journal of Innate Immunity. 2021 | Pubmed ID: 32906119 Isolation and Expansion of Human Limbal Epithelial Progenitor Cells Bio-protocol. Sep, 2020 | Pubmed ID: 33659413 Secreted Phosphoprotein 1 Expression in Retinal Mononuclear Phagocytes Links Murine to Human Choroidal Neovascularization Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 33585455 Arteriovenous Crossing in Retinal Vessels of Mice, Rats, and Pigs Molecular Vision. 2020 | Pubmed ID: 33273800 Corneal Tissue Induces Transcription of Metallothioneins in Monocyte-derived Human Macrophages Molecular Immunology. Dec, 2020 | Pubmed ID: 33137607 Isolation and Enrichment of Melanocytes from Human Corneal Limbus Using CD117 (c-Kit) As Selection Marker Scientific Reports. Oct, 2020 | Pubmed ID: 33067486 Transcriptional Characterization of Conjunctival Melanoma Identifies the Cellular Tumor Microenvironment and Prognostic Gene Signatures Scientific Reports. Oct, 2020 | Pubmed ID: 33046735 Transcriptional Profiling Uncovers Human Hyalocytes As a Unique Innate Immune Cell Population Frontiers in Immunology. 2020 | Pubmed ID: 33042148 CNTF Prevents Development of Outer Retinal Neovascularization Through Upregulation of CxCl10 Investigative Ophthalmology & Visual Science. 08, 2020 | Pubmed ID: 32780864 [What is the Importance of the Conjunctiva As A potential Transmission Pathway for SARS-CoV-2 Infections?] Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft. Jul, 2020 | Pubmed ID: 32572552 3' MACE RNA-sequencing Allows for Transcriptome Profiling in Human Tissue Samples After Long-term Storage Laboratory Investigation; a Journal of Technical Methods and Pathology. Oct, 2020 | Pubmed ID: 32467590 Expression of the COVID-19 Receptor ACE2 in the Human Conjunctiva Journal of Medical Virology. Oct, 2020 | Pubmed ID: 32374427 Transcriptomic Characterization of Human Choroidal Neovascular Membranes Identifies Calprotectin As a Novel Biomarker for Patients with Age-Related Macular Degeneration The American Journal of Pathology. Aug, 2020 | Pubmed ID: 32339498 Temporospatial Distribution and Transcriptional Profile of Retinal Microglia in the Oxygen-induced Retinopathy Mouse Model Glia. Sep, 2020 | Pubmed ID: 32150307 Prevention of Ocular Tenon Adhesion to Sclera by a PDMAA Polymer to Improve Results After Glaucoma Surgery Macromolecular Rapid Communications. Feb, 2020 | Pubmed ID: 31894619 Letter to the Editor Concerning Webber Et al. Exp Eye Res. 148: 97-102, 2016 Experimental Eye Research. Jan, 2019 | Pubmed ID: 28185796 Semaphorin 3F Modulates Corneal Lymphangiogenesis and Promotes Corneal Graft Survival Investigative Ophthalmology & Visual Science. Oct, 2018 | Pubmed ID: 30383199 Increased Expression of Hypoxia-inducible Factor-1 Alpha and Its Impact on Transcriptional Changes and Prognosis in Malignant Tumours of the Ocular Adnexa Eye (London, England). Nov, 2018 | Pubmed ID: 30065361 Activation of Human Macrophages by Human Corneal Allogen in Vitro PloS One. 2018 | Pubmed ID: 29617399 Gene Expression Profiling in a Mouse Model of Retinal Vein Occlusion Induced by Laser Treatment Reveals a Predominant Inflammatory and Tissue Damage Response PloS One. 2018 | Pubmed ID: 29529099 Sema3f Protects Against Subretinal Neovascularization In Vivo EBioMedicine. Apr, 2017 | Pubmed ID: 28373097 Optimizing Rejection Readouts in a Corneal Allograft Transplantation Model Molecular Vision. 2016 | Pubmed ID: 27777504 Systemic Confounders Affecting Serum Measurements of Omega-3 and -6 Polyunsaturated Fatty Acids in Patients with Retinal Disease BMC Ophthalmology. Sep, 2016 | Pubmed ID: 27596098 CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy Investigative Ophthalmology & Visual Science. Aug, 2016 | Pubmed ID: 27494343 Clinical Experience with Eplerenone to Treat Chronic Central Serous Chorioretinopathy Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Nov, 2016 | Pubmed ID: 27145785 MicroRNA Profiling in Aqueous Humor of Individual Human Eyes by Next-Generation Sequencing Investigative Ophthalmology & Visual Science. Apr, 2016 | Pubmed ID: 27064390 Conjunctival Fibrosis Following Filtering Glaucoma Surgery Experimental Eye Research. Jan, 2016 | Pubmed ID: 26675404 Trabeculectomy Versus Canaloplasty (TVC Study) in the Treatment of Patients with Open-angle Glaucoma: a Prospective Randomized Clinical Trial Acta Ophthalmologica. Dec, 2015 | Pubmed ID: 25847610 Genotypes of JC Virus in East, Central and Southwest Europe The Journal of General Virology. May, 2001 | Pubmed ID: 11297697 Investigating Angiogenesis on a Functional and Molecular Level by Leveraging the Scratch Wound Migration Assay and the Spheroid Sprouting Assay Julian Rapp*1,2, Jan Ness*1,3, Paula Liang1, Martin J. Hug4, Hansjürgen Agostini1, Günther Schlunck1, Clemens Lange5, Felicitas Bucher1 1Eye Center, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 2Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 3Institute of Pharmaceutical Sciences, Faculty of Chemistry and Pharmacy, University of Freiburg, 4Pharmacy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 5Ophtha-Lab, Department of Ophthalmology, St. Franziskus Hospital Muenster JoVE 66954 Medicina
Investigating Angiogenesis on a Functional and Molecular Level by Leveraging the Scratch Wound Migration Assay and the Spheroid Sprouting Assay Julian Rapp*1,2, Jan Ness*1,3, Paula Liang1, Martin J. Hug4, Hansjürgen Agostini1, Günther Schlunck1, Clemens Lange5, Felicitas Bucher1 1Eye Center, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 2Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 3Institute of Pharmaceutical Sciences, Faculty of Chemistry and Pharmacy, University of Freiburg, 4Pharmacy, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 5Ophtha-Lab, Department of Ophthalmology, St. Franziskus Hospital Muenster JoVE 66954 Medicina
