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机器人钻孔开颅术对小鼠颅窗手术热损伤的评估

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Neurowissenschaften

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JoVE Journal Neurowissenschaften

Assessment of Thermal Damage from Robot-Drilled Craniotomy for Cranial Window Surgery in Mice

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机器人钻孔开颅术对小鼠颅窗手术热损伤的评估

1,734 Views

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09:30 min

•

November 11, 2022

DOI:

10.3791/64188-v

DOI:

10.3791/64188-v

•

09:30 min

November 11, 2022

•

2 Views

George F. Hoeferlin*^1,2, Dhariyat M. Menendez*^1,2, Olivia K. Krebs^1,2, Jeffrey R. Capadona^1,2, Andrew J. Shoffstall^1,2

¹Department of Biomedical Engineering,Case Western Reserve University, ²Advanced Platform Technology Center,Louis Stokes Cleveland VA Medical Center

Summary

颅窗已成为一种普遍实施的手术技术，允许在转基因小鼠中进行活体成像。该协议描述了手术机器人的使用，该机器人对颅窗进行半自动骨钻孔，可以帮助减少外科医生之间的变异性并部分减轻热血脑屏障损伤。

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