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EGFR 돌연변이 NSCLC 환자 유래 오가노이드에서 표적 치료법에 대한 민감도 프로파일링

JoVE Journal
Krebsforschung

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JoVE Journal Krebsforschung

Profiling Sensitivity to Targeted Therapies in EGFR-Mutant NSCLC Patient-Derived Organoids

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EGFR 돌연변이 NSCLC 환자 유래 오가노이드에서 표적 치료법에 대한 민감도 프로파일링

3,451 Views

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08:52 min

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November 22, 2021

DOI:

10.3791/63039-v

DOI:

10.3791/63039-v

•

08:52 min

November 22, 2021

•

2 Views

Dora Barbosa Rabago^2,3, Collin M. Blakely², Franziska Haderk^2,3, Trever G. Bivona^2,3

¹Department of Medicine,University of California, San Francisco, ²Helen Diller Family Comprehensive Cancer Center,University of California, San Francisco, ³Department of Cellular and Molecular Pharmacology,University of California, San Francisco

Tags

Organoids EGFR-mutant NSCLC Targeted Therapies Matrigel Cell Culture Dissociation Trypsinization Centrifugation Cell Counting Cell Suspension 96-well Plate

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