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实时研究全血-内皮相互作用和血栓动力学的体外微流体疾病模型
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May 24, 2020
DOI:
1Department of Pulmonary Diseases, Amsterdam UMC,VU University Medical Center, Amsterdam Cardiovascular Sciences (ACS), 2BIOS Lab-on-a-Chip group,University of Twente, 3Applied Stem Cell Technologies Group,University of Twente, 4Department of Cardio-thoracic Surgery, Amsterdam UMC,VU University Medical Center, 5Institute of Physiology,Charité-Universitätsmedizin, 6German Heart Center
Summary
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我们提出了一个体外血管疾病模型，以研究整个血液与患者衍生的内皮的相互作用。该系统允许研究各种情况下原发内皮细胞的血栓特性。该方法特别适用于凝血不同阶段的原位血栓形成性和抗凝治疗。
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Cite this Article
Manz, X. D., Albers, H. J., Symersky, P., Aman, J., van der Meer, A. D., Bogaard, H. J., Szulcek, R. In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time. J. Vis. Exp. (159), e61068, doi:10.3791/61068 (2020).
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