/

Entwicklungsbiologie

/

改良多向分化效力的常规人多能干细胞的化学逆转与幼稚样态

JoVE Journal
Entwicklungsbiologie

Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich. Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.

JoVE Journal Entwicklungsbiologie

Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency

Please note that all translations are automatically generated. Click here for the English version.

改良多向分化效力的常规人多能干细胞的化学逆转与幼稚样态

9,715 Views

•

09:07 min

•

June 10, 2018

DOI:

10.3791/57921-v

DOI:

10.3791/57921-v

•

09:07 min

June 10, 2018

•

1 Views

Tea Soon Park*¹, Ludovic Zimmerlin*¹, Rebecca Evans-Moses, Elias T. Zambidis

¹Department of Oncology, Division of Pediatric Oncology and Institute for Cell Engineering,Johns Hopkins School of Medicine

Tags

Chemical Reversion Conventional Human Pluripotent Stem Cells Naive-like State Multilineage Differentiation LIF-3i Method Pre-implantation Epiblast Lineage-primed Gene Expression Epigenomic Stability Regenerative Medicine HPSC Differentiation Gene Targeting Interspecies Chimeras LIF-5i Medium Cell Dissociation Feeder-free Culture

Read Article