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实验模型研究酸性后处理对脑缺血的神经保护作用
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Experimental Models to Study the Neuroprotection of Acidic Postconditioning Against Cerebral Ischemia
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实验模型研究酸性后处理对脑缺血的神经保护作用

7,254 Views

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10:13 min

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July 31, 2017

DOI:

10.3791/55931-v

DOI:
10.3791/55931-v

•

10:13 min
July 31, 2017

•

1 Views
, , , , , ,
1Institute of Pharmacology & Toxicology, College of Pharmaceutical Sciences, Department of Pharmacology, Key Laboratory of Medical Neurobiology of The Ministry of Health of China, Zhejiang Province Key Laboratory of Neurobiology,Zhejiang University

Summary

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酸性后处理可防止脑缺血。在这里我们提出两个模型来执行APC。分别通过体外氧葡萄糖剥夺后将皮质硬膜下切片转移到酸性缓冲液中，并在体内大脑中动脉闭塞后吸入20％CO 2 。

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Zheng, Y., Shen, Z., Wu, X., Jiang, L., Hu, W., Chen, Z., Zhang, X. Experimental Models to Study the Neuroprotection of Acidic Postconditioning Against Cerebral Ischemia. J. Vis. Exp. (125), e55931, doi:10.3791/55931 (2017).

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