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In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging
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In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging
1Wellman Center for Photomedicine,Massachusetts General Hospital, Harvard Medical School, 2Department of Medical Oncology,Beijing Institute of Translational Medicine, Chinese Academy of Sciences, 3Cancer Center, Aviation General Hospital, Beijing, 4Infectious Disease Service,Brooke Army Medical Center
Kapitel
- 00:05Titel
- 01:38Mouse Model of Burn Infection Caused by Bioluminescent A. baumannii
- 03:04Bioluminescence Imaging of Infections in Mice
- 04:27Antimicrobial Blue Light Therapy for A. baumannii Infection in Mice
- 06:51Results: Antimicrobial Blue Light Therapy for A. baumannii Burn Infections
- 08:21Conclusion
Infections caused by multidrug-resistant (MDR) bacterial strains have emerged as a serious threat to public health, necessitating the development of alternative therapeutics. We present a protocol to evaluate the effectiveness of antimicrobial blue light (aBL) therapy for MDR Acinetobacter baumannii infections in mouse burns by using bioluminescence imaging.
