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Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis
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JoVE Journal Neurowissenschaften
Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis

Measuring Progressive Neurological Disability in a Mouse Model of Multiple Sclerosis

DOI:
10.3791/54616-v

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08:11 min

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November 14, 2016

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, ,
1Department of Neurology,Geisel School of Medicine at Dartmouth

Kapitel

  • 00:05Titel
  • 01:14Rotarod Training
  • 03:08Mouse TMEV Infection
  • 04:37Rotarod Experiment
  • 06:12Results: Rotarod Performance Test Shows Lower NFI Values in TMEV-infected MIce Compared to Sham-controls
  • 07:02Conclusion

Summary

Automatische Übersetzung

Automatische Übersetzung

An optimized testing protocol is presented in this paper for the Rotarod performance test, used for measuring progressive neurological disability in TMEV-infected mice.

Tags

Keywords: Mouse ModelMultiple SclerosisProgressive Neurological DisabilityRotarod TestTheilers VirusMotor FunctionBalance CoordinationAcclimationTraining ProtocolTime To FallTrials

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