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Zebrafish의에서 에탄올에 의한 섬유 성 간 모델의 개발은 전구 세포 매개 간세포의 재생을 연구하는
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Entwicklungsbiologie
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JoVE Journal Entwicklungsbiologie
Development of an Ethanol-induced Fibrotic Liver Model in Zebrafish to Study Progenitor Cell-mediated Hepatocyte Regeneration
Please note that all translations are automatically generated. Click here for the English version.

Zebrafish의에서 에탄올에 의한 섬유 성 간 모델의 개발은 전구 세포 매개 간세포의 재생을 연구하는

9,019 Views

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10:42 min

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May 13, 2016

DOI:

10.3791/54002-v

DOI:
10.3791/54002-v

•

10:42 min
May 13, 2016

•

1 Views
, ,
1School of Biology, Parker H. Petit Institute for Bioengineering and Bioscience,Georgia Institute of Technology

Summary

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Sustained fibrosis with deposition of excessive extracellular matrix proteins leads to cirrhosis. Alcohol abuse is one of the main causes of severe liver disease. We established an ethanol-induced zebrafish fibrotic liver model to study the mechanisms and strategies of promoting hepatocyte regeneration upon alcohol-induced injury.

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Huang, M., Xu, J., Shin, C. H. Development of an Ethanol-induced Fibrotic Liver Model in Zebrafish to Study Progenitor Cell-mediated Hepatocyte Regeneration. J. Vis. Exp. (111), e54002, doi:10.3791/54002 (2016).

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