The storage conditions of platelet products create an ideal environment for bacterial contaminants to multiply to dangerous levels. The goal of this study was to use a colony forming assay to evaluate a riboflavin based pathogen reduction process against high titer bacterial contamination in human platelet products.
Keil, S. D., Hovenga, N., Gilmour, D., Marschner, S., Goodrich, R. Treatment of Platelet Products with Riboflavin and UV Light: Effectiveness Against High Titer Bacterial Contamination. J. Vis. Exp. (102), e52820, doi:10.3791/52820 (2015).