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Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
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Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

10,306 Views

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08:42 min

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May 19, 2015

DOI:

10.3791/52061-v

DOI:
10.3791/52061-v

•

08:42 min
May 19, 2015

•

8 Views
, , , ,
1Department of Psychiatry and Behavioural Neurosciences,McMaster University, 2McMaster Integrative Neuroscience Discovery and Study,McMaster University, 3Department of Psychiatry,University of Calgary, 4Department of Psychology, Neuroscience & Behaviour,McMaster University

Summary

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We aim to identify the neural correlates underlying sustained and transient thought suppression, and thought re-emergence in controls, at-risk and depressed individuals. Activation was greatest for controls compared to the at-risk and the depressed group in the dorsolateral prefrontal cortex during thought suppression and anterior cingulate cortex during thought re-emergence.

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FMRIThought SuppressionDepressionRuminationDorsolateral Prefrontal CortexAnterior Cingulate CortexAt-riskMajor Depressive Disorder

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Carew, C. L., Tatham, E. L., Milne, A. M., MacQueen, G. M., Hall, G. B. Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression. J. Vis. Exp. (99), e52061, doi:10.3791/52061 (2015).

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