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Olfactory Assays for Mouse Models of Neurodegenerative Disease
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Neurowissenschaften
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JoVE Journal Neurowissenschaften
Olfactory Assays for Mouse Models of Neurodegenerative Disease

Olfactory Assays for Mouse Models of Neurodegenerative Disease

DOI:
10.3791/51804-v

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07:27 min

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August 25, 2014

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, ,
1Department of Psychology,University of Cincinnati, 2Department of Neurology,University of Cincinnati, 3Department of Neuroscience, Cell Biology, and Physiology,Wright State University

Kapitel

  • 00:05Titel
  • 01:21Buried Pellet Test
  • 03:15Block Test
  • 05:26Habituation/Dishabituation
  • 06:18Results: Olfactory Assays for Mouse Models of Neurodegenerative Disease
  • 06:52Conclusion

Summary

Automatische Übersetzung

Automatische Übersetzung

Impairment in olfactory function is a common feature in many neurodegenerative disorders including Parkinson, Alzheimer, and Huntington diseases. In the present article, we describe a set of tests for assessing olfaction discrimination and detection in mice that can be used to measure olfactory abilities in mouse models of neurodegenerative diseases.

Tags

Olfactory AssaysMouse ModelsNeurodegenerative DiseaseParkinson’s DiseaseOlfactionEarly DetectionNeuroprotective TherapiesRodent ModelsFood OdorsSocial OdorsNon-social OdorsGenetic Mouse Models

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