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Journal / Bioengineering / Tissue Engineering of a Human 3D in vitro Tumor…
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Bioengineering

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JoVE Journal Bioengineering
Tissue Engineering of a Human 3D in vitro Tumor Test System
 

Tissue Engineering of a Human 3D in vitro Tumor Test System

Article DOI: 10.3791/50460-v • 11:12 min • August 6th, 2013
August 6th, 2013 •
*1, *1, 1, 1, 1, 1, 1
1Department of Tissue Engineering and Regenerative Medicine, University Hospital Würzburg
* These authors contributed equally

Kapitel

Summary
Automatic Translation

Methods to create human 3D tumor tissues as test systems are described. These technologies are based on a decellularized Biological Vascularized Scaffold (BioVaSc), primary human cells and a tumor cell line, which can be cultured under static as well as under dynamic conditions in a flow bioreactor.

Tags

Tissue Engineering Human 3D In Vitro Tumor Test System Cancer Therapeutic Strategies 2D Culture Systems Physiological Conditions Biological 3D Matrices Cell Self-organization Tissue Organization Cell Differentiation Scaffolds Cell-cell Interactions Cancer Tumors Malignant Peripheral Nerve Sheath Tumors (MPNSTs) Decellularized Porcine Jejunal Segment Derived Biological Vascularized Scaffold (BioVaSc) Fibroblasts Microvascular Endothelial Cells (mvECs) S462 Tumor Cell Line Static Culture Small Intestinal Submucosa SIS-Muc Metal Rings Flow Bioreactor System Shear Stress Arterial Oxygen And Nutrient Supply
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