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Rapid Determination of the Thermal Nociceptive Threshold in Diabetic Rats
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Rapid Determination of the Thermal Nociceptive Threshold in Diabetic Rats
Kapitel
- 00:05Titel
- 01:15Equipment Set-up
- 02:35Testing Normal Animals
- 04:11Nociceptive Behaviors in Control and Diabetic Animals
- 05:23Conclusion
Here, we describe a rapid reliable and simple procedure to determine the lowest temperature at which rats or mice show nocifensive behavior, i.e. the thermal nociceptive threshold (TNT). This method applies a slowly increasing thermal stimulus allowing precise and reproducible estimation of TNTs with minimum, if any, stress to the animals.
Tags
Thermal Nociceptive ThresholdDiabetic RatsPainful Diabetic NeuropathyHyperalgesiaAllodyniaRodent Models Of Diabetes MellitusBehavioral ResponsesNoxious Thermal StimuliReproducibilityPharmacological SensitivityHot-plate MethodReflex LatenciesSupra-threshold TemperaturesBölcskei Et Al.Rapid DeterminationSensitive And ReproducibleThermal StimulusPlantar Surface
