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Yanal Akışkan Perküsyon: Travmatik Beyin Hasarı Farelerde Modeli
1Department of Neuroscience and Cell Biology,University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, 2Spinal Cord and Brain Injury Research Center, 3Department of Anatomy and Neurobiology, Department of Physical Medicine and Rehabilitation,University of Kentucky Chandler Medical Center
Kapitel
- 00:05Titel
- 01:23Craniectomy
- 05:46Induction of Injury
- 08:19Cognitive, Motor and Histological Outcomes
Yanal sıvı perküsyon (LFP), farelerde travmatik beyin hasarı oluşturulmuş bir model olduğunu göstermiştir. LFP hayvan modellerinde üç ana kriterleri yerine getirir: geçerliliği, güvenilirliği ve klinik önemi. Cerrahi kraniotomi oluşan prosedür, hub tespit, fokal ve diffüz yaralanma ile sonuçlanan yaralanma indüksiyonu ile takip açıklanmıştır.
Tags
Lateral Fluid PercussionTraumatic Brain InjuryTBI ResearchHead InjuriesMorbidityMortalityPrimary InjurySecondary ConsequencesRegenerative ProcessesContusionSkull FractureShearingStretchingDisplacement Of BrainHematomasLacerationsVascular ResponseWhite Matter DamageDiffuse Axonal InjuryEdemaIncreased Intracranial PressureMicroscopic AlterationsExcitotoxic NeurotransmittersImmune MediatorsOxygen RadicalsLong-term Neurological DisabilitiesAnimal Models Of TBICellular EventsMolecular Events
