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1Department of Cell Biology and Anatomy, College of Medicine,University of Arizona, Tucson, 2Southern Arizona Veterans Affairs Health Care System,Tucson, AZ, 3Department of Surgery, College of Medicine,University of Arizona, Tucson, 4Biomedical Diagnostics and Research,Tucson, AZ, 5Department of Medicine, College of Medicine,University of Arizona, Tucson
Kapitel
- 00:05Titel
- 01:47Introduction
- 03:04Preparing Tissues
- 04:15Immunostaining
- 08:16Evaluating Tissue Sections
- 27:11Conclusion
Ridotta espressione / assenza di PMS2 e / o ERCC1 nelle cripte intero è un evento frequente nel raggio di 10 cm su ogni lato degli adenocarcinomi del colon, probabilmente in base ad un difetto del campo con elevata mutevolezza e la progressione del cancro. Carenza di Ku86 o CcOI è molto meno frequente in questi difetti del campo.
Tags
Deficient Pms2Deficient ERCC1Deficient Ku86Deficient CcOIField DefectColon CancerCarcinogenesisMolecular AbnormalitiesColonic AdenocarcinomaAdenoma With Advanced NeoplasiaImmunohistochemistryDNA Repair ProteinsApoptosisDNA Mismatch RepairDNA Nucleotide Excision RepairApoptosis ResistanceMutabilityProgression To Colon CancerDNA Non-homologous End JoiningCytochrome C Oxidase Subunit
