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Chapter 30

細胞の分極と移動

Chapter 30

Cell Polarization and Migration

Cell migration is a process by which the cells move from one location to another, playing an essential role in embryological development, repair and …
Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. …
Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, …
Invadosome is a broad category of cell surface structures with proteolytic activity that  degrades the extracellular matrix (ECM). Invadosomes are …
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or …
Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including …
Myosins are multimeric motor proteins involved in various cellular processes such as migration, adhesion, and proliferation. Myosin II is the most common …
Cell polarity is the asymmetric distribution of cellular and membrane components, making one side of the cell different from the other. This polarity is …
Cells can detect chemical cues in their environment and reorganize the cytoskeleton to migrate toward them or away from them. This directional migration, …
A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles …
The protrusion of the cell surface is an initial step for several cellular processes, including cell migration, phagocytosis, and neurite outgrowth. These …
Migration is a key property of live cells and critical for normal development, immune response, and disease processes such as cancer metastasis and …
Cells respond to chemokine stimulation by losing their round shape in a process called polarization, and by altering the subcellular localization of many …
Myosin proteins bind and interact with filamentous actin (F-actin) and are found in organisms across the phylogenetic tree. Their structure and enzymatic …