High Point University 1 article published in JoVE Biochemistry Examining the Dynamics of Cellular Adhesion and Spreading of Epithelial Cells on Fibronectin During Oxidative Stress Caitlin E Tolbert1, Lindsey Palmquist2, Hannah Lee Dixon2, Melissa C. Srougi2,3 1Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, 2Department of Chemistry, High Point University, 3Biotechnology Program and the Department of Molecular Biomedical Sciences, North Carolina State University This method is useful for quantifying the early dynamics of cellular adhesion and spreading of anchorage-dependent cells onto the fibronectin. Furthermore, this assay can be used to investigate the effects of altered redox homeostasis on cell spreading and/or cell adhesion-related intracellular signaling pathways.