Murine Model for Studying Leptomeningeal Disease Using Circulating Tumor Cells
1Department of Tumor Biology,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, 2Department of Neuro-Oncology,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, 3Department of Cancer Physiology,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute, 4Department of Comparative Medicine,University of South Florida, H. Lee Moffitt Cancer Center & Research Institute
Summary
This article describes a protocol for the propagation of cerebral spinal fluid-circulating tumor cells (CSF-CTCs) collected from patients with melanoma-associated leptomeningeal disease (M-LMD) to develop preclinical models to study M-LMD.
