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Selective Gene Silencing in the Choroid Plexus

Selective Gene Silencing in the Choroid Plexus

June 16, 2023

Eliminación selectiva de genes en el plexo coroideo

Eliminación específica de ChP de A_2ARs con AAV2/5-shRNA y sistema Cre/LoxP

Yuwen Yang*¹, Chenxing Qi*¹, Lanxin Hu¹, Cheng Zheng¹, Xuhang Li¹, Wu Zheng¹, Yiyun Weng², Haiyan Lin^3,4

¹State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital,Wenzhou Medical University, ²Department of Neurology,the First Affiliated Hospital of Wenzhou Medical University, ³Rehabilitation Medicine Center,The Second Affiliated Hospital of Wenzhou Medical University, ⁴Integrative & Optimized Medicine Research Center, China-USA Institute for Acupuncture and Rehabilitation,Wenzhou Medical University

Summary

Aquí, describimos un método para alterar selectivamente las expresiones génicas en el plexo coroideo mientras se evita cualquier impacto en otras áreas del cerebro.

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