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Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition
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神经科学
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JoVE 杂志 神经科学
Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition

Measuring Contralateral Silent Period Induced by Single-Pulse Transcranial Magnetic Stimulation to Investigate M1 Corticospinal Inhibition

DOI:
10.3791/64231-v

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07:33 min

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August 23, 2022

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, , , , , , , , , , ,
1Neuromodulation Center and Center for Clinical Research Learning, Spaulding Rehabilitation Hospital and Massachusetts General Hospital,Harvard Medical School, 2Universidad de Investigación para la Generación y Síntesis de Evidencia en Salud, Universidad San Ignacio de Loyola, 3Research and Development,Soterix Medical, 4City College of New York

Chapters

  • 00:05Introduction
  • 01:00Experimental Procedures
  • 06:18Results: MEP in the EMG Recording of the Target Muscle
  • 07:02Conclusion

Summary

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Contralateral silent period (cSP) assessment is a promising biomarker to index cortical excitability and treatment response. We demonstrate a protocol to assess cSP intended for studying M1 corticospinal inhibition of upper and lower limbs.

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Contralateral Silent PeriodTranscranial Magnetic StimulationM1 Corticospinal InhibitionFDI MuscleEMGMuscle ContractionHotspot

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