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Urokinase-type Plasminogen Activator-induced Mouse Back Pain Model
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Urokinase-type Plasminogen Activator-induced Mouse Back Pain Model

Urokinase-type Plasminogen Activator-induced Mouse Back Pain Model

DOI:
10.3791/63997-v

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06:20 min

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September 01, 2023

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, , ,
1Department of Anesthesiology & Critical Care Medicine,University of New Mexico Health Sciences Center

Chapters

  • 00:00Introduction
  • 00:35Induction of Chronic Back Pain Model
  • 01:55Behavioral Assays
  • 05:08Results: Nociceptive‐Related Behavioral Testing and Data Analysis
  • 05:56Conclusion

Summary

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Methods for simple, rapid induction of a back pain model in mice are provided here using an intraligament injection of urinary plasminogen activator.

Tags

UrokinasePlasminogen ActivatorMouseBack PainNon-invasiveChronic PainLigament InjectionMechanical StimulationHargreaves TestCold Plate Test

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