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Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
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May 26, 2021
DOI:
1Department of Biochemistry and Molecular Genetics,University of Virginia School of Medicine, 2Department of Cardiology, Xinqiao Hospital,Army Medical University, 3Department of Cardiology,Osaka City University Graduate School of Medicine, 4Hematovascular Biology Center, Robert M. Berne Cardiovascular Research Center,University of Virginia School of Medicine
Summary
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We describe three methods of bone marrow transplantation (BMT): BMT with total-body irradiation, BMT with shielded irradiation, and BMT method with no pre-conditioning (adoptive BMT) for the study of clonal hematopoiesis in mouse models.
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Park, E., Evans, M. A., Doviak, H., Horitani, K., Ogawa, H., Yura, Y., Wang, Y., Sano, S., Walsh, K. Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis. J. Vis. Exp. (171), e61875, doi:10.3791/61875 (2021).
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